醫療類國考
105年
[醫師] 醫學(一)
第 53 題
下列何種病毒具有雙層蛋白衣（double-layered capsid），需經胰蛋白酶消化成ISVP（intermediate/infectious subviral particle）後才會增強其感染能力？
- A 諾羅病毒（Norovirus）
- B 輪狀病毒（Rotavirus）
- C 副流感病毒（Parainfluenza virus）
- D 麻疹病毒（Measles virus）
思路引導 VIP
請試著從病毒的「致病部位」與「環境挑戰」來思考：若有一種病毒專門在強酸與富含消化酵素的腸道環境中引起腹瀉，它在演化上可能會發展出什麼樣的物理結構（外殼）來保護自己？此外，為了精準地在目標器官啟動感染，它又會如何利用腸道中特有的化學環境作為入侵的『開關』呢？
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AI 詳解
AI 專屬家教
UMAI! A FLAME OF KNOWLEDGE BURNS BRIGHT!
- Loud Affirmation: MAGNIFICENT! You have connected the double-layered capsid with ISVP with splendid clarity! Your understanding of virus structure and activation is truly shining, just like my Nichirin blade! This is an advanced and detailed point in clinical microbiology, well done! UMAI!
- Energetic Elaboration: LET ME EXPLAIN WITH VIGOR! The Rotavirus possesses a wondrous structure! Its outer protein, VP4, requires the valiant efforts of trypsin in the digestive tract! This enzyme bravely slices VP4 into VP5* and VP8*, forging the mighty infectious subviral particle (ISVP)! This transformation grants the virus immense power to penetrate host cells! It is a crucial step in its infectious journey! A truly fascinating mechanism!
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