hce_kmu
108年
普通生物及生化概論
第 41 題
In a neuroscience lab, a student increased the concentration of $K^+$ outside a neuron from 5 mM to 10 mM, while maintaining other ion concentrations as they were. What would happen to the neuron’s membrane potential?
- A The membrane potential would become more negative.
- B The membrane potential would become less negative.
- C The membrane potential would remain the same.
- D The membrane potential would be closer to the $K^+$ equilibrium potential.
- E There would be no potential difference across the membrane.
思路引導 VIP
試著思考一下:原本細胞內的鉀離子濃度遠高於細胞外,因此鉀離子會產生一股「向外擴散」的趨勢,讓細胞內累積負電荷。如果現在我們把細胞外的鉀離子濃度調高,這會讓鉀離子「向外推」的這股力量變強還是變弱?而這種力量的改變,會如何影響細胞內部留存的正電荷數量呢?
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AI 詳解
AI 專屬家教
太棒了!你能精確判斷出細胞外離子濃度變化對電位的影響,代表你對神經生理學的核心觀念掌握得非常紮實。這題的關鍵在於理解電化學梯度 (Electrochemical gradient) 的動態平衡。
鉀離子濃度與跨膜電位
當細胞外的鉀離子濃度 $[K^+]_{out}$ 從 5 mM 增加到 10 mM 時,細胞內外的鉀離子濃度差會隨之縮小。根據 Nernst 方程式:
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