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hce_kmu 108年 物理及化學

第 78 題

As shown below, compound IV can be prepared from reagents I, II, and III. Which of the following reaction conditions is the most suitable for the preparation of IV?
題目圖片
  • A I is slowly added to II, and III is then added to the above mixture.
  • B I is slowly added to II, and the resultant mixture is slowly added to III.
  • C II is slowly added to I, and III is then added to the above mixture.
  • D II is slowly added to I, and the resultant mixture is slowly added to III.
  • E I is slowly added to III, and II is then added to the above mixture.

思路引導 VIP

請思考一下:如果我們在反應瓶裡已經準備好了強鹼 LDA,但隨後要加入的兩個化學物質(化合物 I 與 III)其實都擁有可以被鹼拔走的氫原子,我們該採取什麼樣的順序,才能確保只有「我們想要的那個分子」被鹼反應,而不會讓強鹼在第二個分子加入時,還留在瓶子裡『找錯對象』呢?

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