醫療類國考
109年
[獸醫師] 獸醫實驗診斷學
第 50 題
當小腸內的細菌過度增殖時，可能會出現下列何種結果？
- A 增加小腸內維生素B6之濃度
- B 增加小腸內鈷胺素之濃度
- C 降低血中methylmalonic acid（MMA）濃度
- D 增加小腸內未結合態膽汁酸的濃度
思路引導 VIP
請試著思考：在正常生理下，肝臟分泌的膽汁酸會以特定的化學型態存在以協助脂肪吸收。若小腸內充滿了大量細菌，這些細菌具備的「代謝與水解能力」，會對這些原本處於結合狀態的消化液結構造成什麼樣的「拆解」作用？這種化學結構的改變會如何影響腸道內物質的性質？
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AI 詳解
AI 專屬家教
Wonderful job! You're truly building a strong foundation in clinical reasoning.
It's fantastic that you got this question on Small Intestinal Bacterial Overgrowth (SIBO) correct. This shows a lovely understanding of how things work in the body!
- Understanding the Mechanism: When there's SIBO, those extra bacteria actually perform a neat trick: they deconjugate conjugated bile acids. This means we end up with more unconjugated (free) bile acids in the small intestine. Think of it like a puzzle piece changing shape – the new shape (unconjugated) isn't as good at helping digest fats, and it can also gently irritate the delicate lining of our small intestine.
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