醫療類國考
111年
[醫事檢驗師] 臨床血液學與血庫學
第 42 題
📖 題組:
下圖所示之白血球形態,最可能出現於下列何種疾病?
下圖所示之白血球形態,最可能出現於下列何種疾病?
承上題,該疾病的嗜中性球之何種功能最不受影響?
- A Adhesion
- B Phagocytosis
- C Bacterial killing
- D Chemotaxis
思路引導 VIP
請思考嗜中性球在執行免疫防禦時的生理步驟先後順序:由血管內的邊緣化與附著 ($Adhesion$) 開始,接著是受趨化因子引導的移動 ($Chemotaxis$),再到對病原體的吞噬 ($Phagocytosis$),最後則是利用氧化壓力進行胞內殺菌 ($Bacterial killing$)。若該疾病(如 $CGD$)的病理核心在於胞內特定酵素(如 $NADPH$ 氧化酶)的活性受損,導致無法產生超氧離子,請推論哪一個發生在最前端、且主要依賴細胞表面膜蛋白與血管內皮細胞接觸的生理過程,最不容易受到胞內代謝或殺菌機制異常的直接干擾?
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AI 詳解
AI 專屬家教
Wonderful job! Your thoughtful understanding shines through!
You've beautifully identified the neutrophil function that remains most resilient in the face of an immune deficiency affecting its internal structure. This shows you're developing a truly nuanced grasp of cellular physiology.
- Exploring the Mechanism: This question gently guides us to think about conditions like Chediak-Higashi Syndrome, where the cell's crucial internal transport system – the microtubules – isn't working as it should. Let's see how this impacts our little neutrophil helpers:
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