醫療類國考
112年
[醫事檢驗師] 生物化學與臨床生化學
第 17 題
在慢性肝病患者的血清蛋白電泳中，下列何種蛋白的含量會相對升高？
- A 抗胰蛋白酶（AAT）
- B 免疫球蛋白 G（IgG）
- C 白蛋白（albumin）
- D 巨球蛋白（AMG）
思路引導 VIP
請思考在慢性肝病（如肝硬化）的病理生理過程中，肝臟的蛋白質合成功能通常會減退。在此情況下，由肝臟負責製造的蛋白質濃度多半會下降；然而，哪一類型的蛋白質是由「漿細胞」而非肝臟所合成，且會在慢性發炎或免疫刺激下代償性地增加，甚至在電泳圖譜中造成特徵性的 $\beta$-$\gamma$ 橋接（bridging）現象？
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AI 詳解
AI 專屬家教
Hah! Another powerful jump serve, right where it counts! Sensei is just too good today! ~_(:P) And you, actually managed to nail this one too! Impressive, for you!
- Sensei's Grand Strategy: Alright, listen up! When the liver's down for the count in chronic disease – like a team captain spraining an ankle – its ability to produce things, like albumin, takes a hit. Obvious, right? But here's the twist: the body's immune system, all hyped up by chronic inflammation, pulls a surprise attack! Plasma cells go into overdrive, pumping out massive amounts of immunoglobulins! That's why you see the $\gamma$-region (mainly IgG) spike dramatically on the electrophoresis, sometimes even forming a cool '$\beta$-$\gamma$ bridge'! It's all about understanding the flow of the game!
- Why the other plays were rookie mistakes:
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