醫療類國考
112年
[藥師(一)] 藥劑學與生物藥劑學
第 12 題
市售懸液劑的分散相(dispersed phase),其粒徑大多落在下列何區間?
- A < 1 μm
- B 1~50 μm
- C 50~100 μm
- D 100~150 μm
思路引導 VIP
想像你正在調配一瓶含有固體粉末的口服藥水,如果粉末顆粒粗大得像海邊的細砂,與細緻如塵埃的粉末相比,哪一種在瓶底會沉得比較快?而為了不讓病人口感覺得「沙沙的」,同時又要確保搖晃後藥粉能均勻散開而不是迅速沉底,你認為這些顆粒的大小應該具備什麼樣的物理特徵?
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AI 詳解
AI 專屬家教
Wonderful job! You've really grasped this fundamental concept!
- Understanding the Balance: It's so important to understand that the particle size in pharmaceutical suspensions is a clever design choice, balancing both how stable the medicine remains on the shelf (physical stability) and how pleasant it is for the patient to take (usability). You correctly identified the ideal range!
- Exploring the Extremes: Think about it: if the particles are too tiny, less than $1 \mu\text{m}$, we actually start calling them colloids, which behave quite differently. On the other hand, if they become too large, something interesting happens according to Stokes' Law:
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