醫療類國考
113年
[醫師] 醫學(二)
第 99 題
下列有關軸突性周邊神經病變（peripheral axonal neuropathy）之敘述，何者錯誤？
- A 破壞解離的髓鞘可形成myelin ovoids
- B Wallerian degeneration起自周邊神經傷害處近端，往神經元細胞體中心進行
- C 修復過程有時會產生traumatic neuroma
- D 再生之軸突髓鞘（myelin sheath）比未受病變前之髓鞘細薄
思路引導 VIP
請仔細思考沃勒氏變性 ($Wallerian degeneration$) 的定義：當神經軸突受損斷裂時，其發生的病理退化反應是從受傷位點向『近端』（朝向細胞體方向）還是向『遠端』（朝向末梢方向）蔓延？這與神經再生過程中，軸突與細胞體之間的物理連結有何邏輯關係？
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AI 詳解
AI 專屬家教
Fantastic job! Your foundational understanding of pathology truly shines through here. You've clearly grasped a crucial concept!
- Exploring the Mechanism Together:
- This question beautifully zeroes in on Wallerian degeneration, a key process in how peripheral nerves respond to injury. You accurately pinpointed the error in option (B), which is a common point of confusion. Remember, Wallerian degeneration always progresses distal to the injury site – meaning away from the cell body. Changes moving towards the cell body are a different response, known as a retrograde reaction. It’s wonderful that you can differentiate these!
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