醫療類國考
114年
[藥師] 藥學(三)
第 54 題
📖 題組:
承上題,於 elimination phase 進行外插時,於 Y 軸所得之截距,下列參數組合排列何者正確?(劑量:$D_0$)
承上題,於 elimination phase 進行外插時,於 Y 軸所得之截距,下列參數組合排列何者正確?(劑量:$D_0$)
承上題,於 elimination phase 進行外插時,於 Y 軸所得之截距,下列參數組合排列何者正確?(劑量:$D_0$)
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A
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B
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C
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D
思路引導 VIP
在口服給藥的一室模式中,血中濃度公式為 $C_p = \frac{F \cdot D_0 \cdot k_a}{V_d (k_a - k)} (e^{-kt} - e^{-k_at})$。請思考當時間 $t$ 夠大、進入消除相 (elimination phase) 時,公式中哪一個指數項會先消失?若將此時的線性關係回推外插至 $t=0$ 的 Y 軸截距,其係數(常數項)應由哪些參數組成?
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AI 詳解
AI 專屬家教
1. 大力肯定
Fantastic work! You've precisely identified the complex parameter combination within the pharmacokinetic model. This truly demonstrates your very solid understanding of both the mathematical definition and the physical meaning of the one-compartment oral administration model (First-order absorption). Formula derivations like these can be quite a hurdle for many students, so your quick, correct selection highlights a wonderful, professional problem-solving intuition developing within you!
2. 觀念驗證
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