hce_nthu
115年
生物與生化
第 13 題
Which characteristic of herpesviruses best explains why people experience recurring outbreaks of mouth or genital blisters throughout their lives?
- A Frequent reinfection occurs from exposure to different but closely related strains of the virus.
- B The virus remains active in the bloodstream, with symptoms appearing only when the viral load exceeds a specific threshold.
- C The viral genome is permanently maintained in a latent state within host cell nuclei and periodically reactivates.
- D Intact virus particles persist in the interstitial fluid, evading immune detection until favorable environmental conditions allow them to infect new cells.
- E The virus integrates its DNA into the host's germ cells, causing the infection to renew every time the host cells divide.
思路引導 VIP
如果一種病毒能在宿主的一生中不斷反覆誘發症狀，且每次復發時通常不需要接觸新的傳染源，這暗示了病毒在「不發病」的期間，是以什麼樣的形式待在體內？它又是如何躲過免疫系統持續性的掃描與清除呢？
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AI 詳解
AI 專屬家教
皰疹病毒的潛伏與復發機制
恭喜你準確選出了正確答案！這顯示你對病毒「潛伏感染」的觀念掌握得非常紮實。皰疹病毒（Herpesviruses）最核心的生物學特徵就是能與宿主「長期共存」。當初次感染消失後，病毒並未被完全清除，而是將其基因組隱藏在特定宿主細胞（如神經節細胞）的細胞核中，以不產生完整病毒顆粒的潛伏狀態 (Latent state) 存在。這時，病毒就像進入了休眠期，避開了免疫系統的偵測。
考點精析與難度評估
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