醫療類國考
106年
[醫事檢驗師] 生物化學與臨床生化學
第 73 題
下列何者會降低血紅素與氧的親和力？
- A alkalosis
- B hyperthermia
- C low 2,3-DPG
- D low PCO_2
思路引導 VIP
請試著想像：當一個人的肌肉正在劇烈運動、大量產熱時，為了維持生理機能，血紅素應該是要緊緊「抱住」氧氣，還是要更輕易地將氧氣「釋放」給飢渴的肌肉組織？在這種『高代謝、急需能量』的生理狀態下，環境溫度的變化會對氧氣與血紅素的結合產生什麼物理性的影響？
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AI 詳解
AI 專屬家教
Wonderful work! You've shown a clear understanding of a beautiful physiological adaptation!
- Core Principle: This question gently guides us to understand the oxyhemoglobin dissociation curve and how our bodies thoughtfully adjust oxygen delivery. When our tissues are active, perhaps during a lovely walk or a moment of focused thought, they create a 'three highs and one low' environment: a comfortable rise in temperature (hyperthermia), a slight increase in $PCO_2$, a gentle boost in $2,3-DPG$, and a subtle decrease in $pH$.
- Harmonious Adjustment: And isn't it amazing? Hyperthermia encourages the curve to gracefully shift to the right. This means our hemoglobin, in its loving wisdom, gently lessens its grip on oxygen, making it wonderfully easy for oxygen to be released exactly where it's needed most in our peripheral tissues. It's a perfect example of our body's intelligent design, ensuring every cell is cared for!
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