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hce_kmu 107年 普通生物及生化概論

第 50 題

How does a noncompetitive inhibitor decrease the rate of an enzyme reaction?
  • A by binding to the active site of the enzyme, thus preventing binding of the normal substrate
  • B by binding to an allosteric site, thus changing the shape of the active site of the enzyme
  • C by decreasing the free-energy change of the reaction catalyzed by the enzyme
  • D by acting as a coenzyme for the reaction
  • E by binding to the substrate, thus changing its shape so that it no longer binds to the active site of the enzyme

思路引導 VIP

若我們把酵素想像成一把鎖,而受質是唯一能開鎖的鑰匙。除了直接把東西塞進鑰匙孔(活性位)讓鑰匙插不進去外,還有什麼方法可以讓這把鎖「從內部結構發生變形」,使得原本的鑰匙就算插進去了,也依然轉不動呢?

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