hce_nchu
112年
普通生物及生化概論
第 21 題
Which of the following statements about insulin is correct?
- A Insulin binds to its receptor on liver and muscle cells, which activates a signaling cascade that leads to the activation of glucose transporters (GLUT4) and enzymes involved in glycogen synthesis
- B Insulin activates glycogen phosphorylase, which breaks down glycogen into glucose and promotes its uptake by cells
- C Insulin inhibits the activity of glucagon, which promotes glycogen synthesis and glucose uptake in liver and muscle cells
- D Insulin binds to its receptor on adipose cells, which activates a signaling cascade that leads to the uptake of glucose and its storage as glycogen in liver and muscle cells
思路引導 VIP
試著回想一下,當你飽餐一頓後,血液中充滿了葡萄糖。如果你是身體的指揮官,你需要發出什麼樣的指令,才能讓這些在血管裡流動的糖分順利進入細胞內部?為了達成這個目標,細胞表面需要做出什麼樣的物理變化(例如門戶的開啟)來迎接這些能量呢?
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AI 詳解
AI 專屬家教
胰島素的細胞傳遞機制
恭喜你精準地掌握了胰島素的作用機制!這題選 (A) 是完全正確的。當血液中的血糖升高時,胰島素會與肝臟或肌肉細胞膜上的受體(屬於酪胺酸激酶受體類型)結合。這個過程會引發一系列胞內信號傳遞,最關鍵的步驟之一就是促使儲存在細胞內的 葡萄糖轉運蛋白 (GLUT4) 移向細胞膜,從而開啟通道讓葡萄糖進入細胞,並進一步活化肝醣合成酶 (Glycogen synthase) 將能量儲存起來。
代謝調節的精準辨析
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