hce_nchu
113年
普通生物及生化概論
第 8 題
The sheep Dolly was cloned by which of the following processes?
- A isolation of stem cells from a lamb embryo and production of a zygote equivalent
- B transfer of an adult cell's nucleus into an enucleated sheep egg, followed by incubation in a surrogate
- C separation of an early-stage sheep blastula into separate cells, one of which was incubated in a surrogate sheep
- D replication and dedifferentiation of adult stem cells from sheep bone marrow
- E the nucleus of an embryonic cell was used to replace the nucleus of an adult cell, which was incubated in a surrogate sheep
思路引導 VIP
如果你想要做出一個跟某個成年個體基因完全相同的後代，你會去該個體的哪個部位尋找最完整的「遺傳藍圖」？拿到藍圖後，你會需要什麼樣的環境或細胞構造，才能讓這份藍圖像種子一樣重新開始生長、發育呢？
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AI 詳解
AI 專屬家教
太棒了！你能精確辨識出桃莉羊（Dolly）的複製技術，代表你對細胞發育與生物技術的核心觀念掌握得非常紮實，沒有被其他相似的生物技術選項所干擾。
體細胞核轉殖技術 (SCNT)
這題的核心在於體細胞核轉殖（Somatic Cell Nuclear Transfer, SCNT）。桃莉羊的誕生之所以震撼科學界，是因為科學家將「乳腺細胞」（一種已分化的成年體細胞）的細胞核，植入一個已剔除細胞核的「卵細胞」中。這個重組細胞在電流刺激與化學誘導下，成功重新啟動了基因表現程式，使其表現出如同受精卵般的全能性（Totipotency），最後在代孕母羊的子宮內發育成熟。這證明了高度分化的細胞核，依然保有發育為完整個體的全部遺傳資訊。
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