真核生物基因表現的轉錄調控與轉錄後修飾

📝 歷屆考古題

• 115年 hce_nchu 第15題
  In eukaryotic gene transcription, which of the following is a core promoter sequence most frequently…
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• 115年 hce_nchu 第36題
  During DNA replication and transcription, the unwinding of the double helix creates overwinding tens…
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• 115年 hce_nchu 第51題
  During gene transcription, E. coli RNA polymerase exists in both core enzyme and holoenzyme states.…
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• 115年 hce_nchu 第53題
  The telomeres at the ends of chromosomes contain single-stranded DNA sequences rich in guanine. What…
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• 115年 hce_nchu 第54題
  The "Holliday Model" describes a series of steps for homologous recombination. What is the correct t…
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• 115年 hce_nchu 第68題
  In the eukaryotic DNA repair mechanism, which of the following enzymes is responsible for catalyzing…
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• 115年 hce_nchu 第69題
  Peptidyltransferase catalyzes the formation of the peptide bond. According to the structural analysi…
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• 114年 hce_nchu 第27題
  Which of the following molecules is most similar in structure to ATP?
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• 114年 hce_nchu 第31題
  Which of the following is the antibacterial mechanism of Tetracyclines?
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• 114年 hce_nchu 第50題
  What is the primary function of the enzyme telomerase?
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• 114年 hce_nchu 第53題
  What is the role of topoisomerase in DNA replication?
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• 114年 hce_nchu 第58題
  In prokaryotic translation, which of the following proteins is responsible for binding and transport…
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• 114年 hce_nchu 第64題
  In the context of genetic engineering, which method allows for the precise editing of specific genes…
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• 113年 hce_nchu 第8題
  The sheep Dolly was cloned by which of the following processes?
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• 113年 hce_nchu 第9題
  The insulin gene is transcriptionally expressed in certain pancreatic cells, but not in skin cells.…
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• 113年 hce_nchu 第23題
  A virus consisting of a single strand of RNA, which is reverse transcribed into complementary DNA, i…
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• 113年 hce_nchu 第25題
  Which of the following is a role of specific transcription factors?
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• 113年 hce_nchu 第26題
  How can cells with the same genes come into being unambiguously dissimilar cell types with specializ…
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• 113年 hce_nchu 第27題
  All of the following groups, when added to histones, can result in an enhanced transcription EXCEPT
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• 113年 hce_nchu 第28題
  What does the binding of a probe to the membrane in a Northern blot indicate
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• 113年 hce_nchu 第29題
  What governs the sequence by which tRNAs convey amino acids to mRNA
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• 113年 hce_nchu 第30題
  Producing 100,000 different proteins from 20,000 genes delineates
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• 113年 hce_nchu 第31題
  What is the molecular event by which the operator of an operon regulates the expression of its struc…
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• 113年 hce_nchu 第33題
  A 10-year-old girl is brought by her parents to the dermatologist. She has many freckles on her face…
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• 113年 hce_nchu 第34題
  During RNA synthesis, the DNA template sequence TAGC would be transcribed to produce which of the fo…
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• 113年 hce_nchu 第35題
  Methylation and subsequent deamination of cytosine produces what type of mutation after one round of…
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• 113年 hce_nchu 第36題
  As a measure of quality control in translation, which component of the translation machinery is capa…
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• 113年 hce_nchu 第37題
  The hydrogen bonding interactions in a Watson-Crick AT base-pair involve what units in the adenine b…
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• 113年 hce_nchu 第38題
  Splice sites in pre-mRNA are marked by two universally conserved sequences contained
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• 113年 hce_nchu 第39題
  An isolate of a mutant bacterium appears to grow more slowly than the wild-type population from whic…
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• 113年 hce_nchu 第40題
  Which of the following molecules can be considered a final product in the flow of genetic informatio…
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• 113年 hce_nchu 第41題
  Which of the following is not a reason for the importance of mRNA processing in eukaryotes?
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• 113年 hce_nchu 第42題
  Of the following steps associated with translation, which does not involve hydrolysis of GTP?
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• 113年 hce_nchu 第43題
  In eukaryotes, the \$3'$ end of the mRNA is important in the initiation of translation because
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• 113年 hce_nchu 第44題
  Which of the following statements is not true concerning peptidyl transferase?
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• 113年 hce_nchu 第45題
  Gene knockdown via RNAi relies on the ability of eukaryotic cells to
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• 113年 hce_nchu 第46題
  You are working with a gene associated with an essential pathway that is necessary at two time point…
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• 113年 hce_nchu 第47題
  The amount of a protein in a cell is regulated by the rate of
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• 113年 hce_nchu 第48題
  Release of RNA polymerase II to initiate transcription appears to be the direct result of the
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• 112年 hce_nchu 第44題
  During a transition mutation, an Adenine will be replaced by:
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• 112年 hce_nchu 第45題
  Which one of the following statements best describes the structure of a nucleosome ?
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• 112年 hce_nchu 第46題
  Which one of the descriptions below about RNA polymerase III is correct?
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• 112年 hce_nchu 第47題
  Which of the eukaryotic RNA polymerase below is/are resistant to $\alpha$-amanitin in eukaryotic cel…
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• 112年 hce_nchu 第48題
  Which one of the below is required for RNA splicing to occur?
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• 112年 hce_nchu 第49題
  The function of the soluble translation factor EF-Tu is:
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• 112年 hce_nchu 第50題
  The linkage between the tRNA and an amino acid in an amino-acyl tRNA complex is mediated by?
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• 112年 hce_nchu 第57題
  Watson and Crick built an antiparallel double helix model structure of DNA. Which type of bond holds…
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• 112年 hce_nchu 第58題
  Transcription generates pre-mRNA and undergoes modification with 5'cap and 3' poly-A tail. Which of…
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• 112年 hce_nchu 第60題
  The RNA-guided Cas9 nuclease and clustered regularly interspaced short palindromic repeats (CRISPR)…
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• 112年 hce_nchu 第61題
  Noncoding RNAs play multiple roles in regulating gene expression. Which of the following statements…
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• 112年 hce_nchu 第62題
  Which of the following mechanism is NOT how bacteria defend against phage infection?
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• 111年 hce_nchu 第6題
  Which of the following, when paired with its complementary strand, would have the highest Tm?
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• 111年 hce_nchu 第7題
  Diphtheria toxin kills cells by inactivating EF-2 proteins. Which process is inhibited by the diphth…
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• 111年 hce_nchu 第20題
  About DNA replication in eukaryotic cells, which of the following statement is correct? 1) There are…
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• 111年 hce_nchu 第21題
  Post-translational modifications are critical for the regulation of biological processes. Which of t…
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• 111年 hce_nchu 第22題
  The Crispr/Cas9 is the approach using DNA damage and repair to modify the genomic DNA. Select the ty…
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• 111年 hce_nchu 第23題
  Which of the following is known to be involved in transcription initiation by eukaryotic RNA polymer…
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• 111年 hce_nchu 第25題
  Transcription initiation requires the formation of pre-initiation complex (PIC). Which of followings…
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• 111年 hce_nchu 第26題
  Which of the following antibiotics function by interfering with the translational process? 1) Chlora…
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• 111年 hce_nchu 第27題
  Which of the following is true of the lac operon? 1) It is negatively controlled via the lac repress…
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• 111年 hce_nchu 第28題
  Which of the following is NOT an example of epigenetic regulation? 1) X chromosome inactivation 2) G…
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• 111年 hce_nchu 第50題
  Which of the following statements correctly describes the difference between the leading strand and…
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• 111年 hce_nchu 第51題
  Gene expression is often assayed by measuring the level of mRNA produced from a gene. Which of the f…
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• 111年 hce_nchu 第52題
  Which of the following enzymes is required to make complementary DNA (cDNA) from RNA?
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