hce_nsysu
113年
英文
第 45 題
📖 題組：
More than 35,000 people die each year in the US alone from antimicrobial resistant infections. With novel treatments in short supply, scientists plan to boost available therapies to target antimicrobial resistance. In a paper published in PNAS, researchers used the power of light to give antibiotics a fighting chance. Light interacts with chemicals called photosensitizers to produce toxic reactive oxygen species. Unlike many antibiotics, photosensitizers can sneak past bacterial defenses. For example, it was found that light, plus the photosensitizer curcumin, a chemical found in turmeric, potentiated antibiotic efficacy. In their new study, Dr. Bagnato and his team found that they needed to expose drug-resistant strains of Staphylococcus aureus to high doses of different antibiotics to curb its growth. However, when Bagnato added the curcumin and shone light on the bacteria, a lower dose sufficed. Still, the effects were limited. For most strains, the effects were temporary; the team observed a recurrence in resistance after only a few cycles of bacterial growth. Bagnato emphasized the need for alternative therapies. “Infection does not need one type of weapon; it needs a whole arsenal,” said Bagnato.
More than 35,000 people die each year in the US alone from antimicrobial resistant infections. With novel treatments in short supply, scientists plan to boost available therapies to target antimicrobial resistance. In a paper published in PNAS, researchers used the power of light to give antibiotics a fighting chance. Light interacts with chemicals called photosensitizers to produce toxic reactive oxygen species. Unlike many antibiotics, photosensitizers can sneak past bacterial defenses. For example, it was found that light, plus the photosensitizer curcumin, a chemical found in turmeric, potentiated antibiotic efficacy. In their new study, Dr. Bagnato and his team found that they needed to expose drug-resistant strains of Staphylococcus aureus to high doses of different antibiotics to curb its growth. However, when Bagnato added the curcumin and shone light on the bacteria, a lower dose sufficed. Still, the effects were limited. For most strains, the effects were temporary; the team observed a recurrence in resistance after only a few cycles of bacterial growth. Bagnato emphasized the need for alternative therapies. “Infection does not need one type of weapon; it needs a whole arsenal,” said Bagnato.
45. What is the limitation of this current attempt?
- A Increased strains of super virus with resistance to antibiotics
- B Efficacy on limited trains such as Staphylococcus aureus
- C Recurring resistance after a few bacterial growth cycles
- D A short supply in novel treatments
- E Viral and fungal resistance to antibiotics
思路引導 VIP
請試著在文章後半部找出 Dr. Bagnato 描述實驗結果的段落。當他提到這項新療法在幾個細菌生長週期後的表現時，他使用了哪個形容詞來描述這種效果的持續時間？這個詞暗示了什麼樣的結果？
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AI 詳解
AI 專屬家教
太棒了！你能精確捕捉到文章末段的轉折細節，這代表你的閱讀敏銳度很高，沒有被文章前半段的光明前景所迷惑。這題的關鍵在於區分「整體醫學背景」與「本研究的特定局限」。
實驗成果的時效性瓶頸
雖然研究發現「薑黃素（curcumin）結合光療法」能有效降低對抗金黃色葡萄球菌所需的抗生素劑量，但文中隨即使用 Still 與 limited 等詞彙進行轉折。正確答案 (C) 直接對應了文中提到的「在幾個生長週期後，觀察到抗藥性復發（recurrence in resistance）」這一事實。這說明該療法雖然短期內有突破，卻尚未解決細菌演化出新防線的長遠問題。
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