酵素動力學原理與變構調節機制

📝 歷屆考古題

• 115年 hce_nthu 第34題
  Which kinetic parameter best reflects catalytic efficiency at low substrate concentrations?
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• 115年 hce_nthu 第38題
  An enzyme exhibits normal Michaelis–Menten kinetics at pH 7 but displays sigmoidal kinetics at pH 9.…
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• 115年 hce_nthu 第41題
  A highly active muscle cell is subjected to extreme mechanical work, causing a sharp, sustained acce…
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• 115年 hce_nthu 第42題
  Pepsin is a digestive enzyme that functions optimally at a pH of 2, an environment highly concentrat…
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• 115年 hce_nthu 第60題
  The Henderson-Hasselbalch equation (below) is widely used in biochemistry to calculate the pH of buf…
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• 114年 hce_nthu 第31題
  Which of the following reaction would favor cellular gluconeogenesis in the fasted state?
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• 114年 hce_nthu 第43題
  Which of the following metabolic enzymes is NOT directly regulated by the ATP level?
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• 114年 hce_nthu 第45題
  Which of the following statements accurately describes the Warburg effect?
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• 114年 hce_nthu 第46題
  The following plot is for an enzyme with multiple ligand binding sites. Which statement is True for…
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• 114年 hce_nthu 第47題
  The diagram depicts the mechanism of a protease inhibitor. What is the target of this inhibitor?
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• 114年 hce_nthu 第51題
  Based on the enzyme reaction plot shown below, which of the following statements is correct?
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• 114年 hce_nthu 第52題
  Which of the following statements about the initial step of the reaction catalyzed by thermolysin is…
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• 114年 hce_nthu 第59題
  Which of the following statements about kcat is correct?
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• 113年 hce_nthu 第52題
  This enzyme reaction plot reflects most likely a mechanism of _______.
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• 113年 hce_nthu 第53題
  Which of the following descriptions of the Monod, Wyman, and Changeux model of allosteric enzyme reg…
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• 113年 hce_nthu 第56題
  Glutamate dehydrogenase catalyzes the reaction shown below. In a reaction mixture containing a satur…
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• 113年 hce_nthu 第57題
  Metformin is a drug for the treatment of type 2 diabetes. The drug has a wide action. Which of the f…
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• 112年 hce_nthu 第29題
  Pyruvate kinase is allosterically regulated by several effectors. Which of the following statements…
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• 112年 hce_nthu 第35題
  Which kind of inhibitor increases the apparent affinity of the enzyme for the substrate?
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• 112年 hce_nthu 第41題
  Which of the following statements about AMP-activated protein kinase (AMPK) is incorrect?
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• 112年 hce_nthu 第46題
  Many enzyme-catalyzed reactions involved the formation of low-barrier hydrogen bonds (LBHB). Which o…
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• 112年 hce_nthu 第50題
  Hypoxia condition is a common microenvironment within tumor. Hypoxia might attenuate mitochondrial a…
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• 112年 hce_nthu 第51題
  Pyruvate kinase is one of the regulatory enzymes within glycolytic pathway. However, the genetic def…
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• 111年 hce_nthu 第28題
  Alpha-D-glucose undergoes conversion to beta-D-glucose in solution. If at $300 \text{K}$ there is 70…
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• 111年 hce_nthu 第31題
  The Km and Vmax of hexokinase I for glucose are $100 \mu\text{M}$ and $30 \mu\text{M/min}$ and the K…
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• 111年 hce_nthu 第36題
  The kinetic constants for wild-type and mutant ATPase are listed in the table. Which of the followin…
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• 111年 hce_nthu 第39題
  Which of the following statements about the characteristics of allosteric enzymes is correct?
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• 111年 hce_nthu 第59題
  Chorismate mutase converts chorismate to prephenate. Which of the following is NOT relevant to the r…
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