胺基酸的化學結構特性與功能分類

📝 歷屆考古題

• 115年 hce_kmu 第19題
  A protein is observed to bind its ligand with higher affinity at low pH. What is the most likely exp…
  查看 AI 詳解 →
• 115年 hce_kmu 第65題
  During the first half of the chymotrypsin mechanism where the acyl-enzyme intermediate is formed, wh…
  查看 AI 詳解 →
• 115年 hce_kmu 第76題
  Which one of the following statements is NOT correct?
  查看 AI 詳解 →
• 114年 hce_kmu 第18題
  Which of the following statements about amino acid residues is correct? ① Phenylalanine has UV absor…
  查看 AI 詳解 →
• 114年 hce_kmu 第66題
  Which one of the following amino acid peaks will NOT appear in the HPLC chromatogram for amino acid…
  查看 AI 詳解 →
• 114年 hce_kmu 第71題
  Which of the following enzymes is an aspartate protease and exhibits its catalytic mechanism through…
  查看 AI 詳解 →
• 114年 hce_kmu 第79題
  Phenylketonuria (PKU) and Maple Syrup Urine Disease (MSUD) are both inherited metabolic disorders af…
  查看 AI 詳解 →
• 114年 hce_kmu 第84題
  ① is one of the enzymes that appears in ② . Which one of the following is NOT correct?
  查看 AI 詳解 →
• 112年 hce_kmu 第10題
  Which of the following statements describes pepsin?
  查看 AI 詳解 →
• 112年 hce_kmu 第15題
  There are 20 different amino acids. What makes one amino acid different from another?
  查看 AI 詳解 →
• 112年 hce_kmu 第17題
  Regarding to prion hypothesis, what kind of abnormal protein structures in misfolded prion protein m…
  查看 AI 詳解 →
• 112年 hce_kmu 第20題
  Which amino acid residue must be tagged on by covalent linkage of ubiquitin when proteins are target…
  查看 AI 詳解 →
• 112年 hce_kmu 第22題
  What is the net charge of the following peptide at pH 7.0? Tyr-Glu-Ser-Arg-Met-Thr-Asp-Asn-Tyr-His
  查看 AI 詳解 →
• 112年 hce_kmu 第27題
  Which of the following sets of amino acids are directly involved in the biosynthesis of creatine?
  查看 AI 詳解 →
• 112年 hce_kmu 第28題
  Hydropathy plot is commonly used for ______.
  查看 AI 詳解 →
• 112年 hce_kmu 第68題
  Among 9 different molecules below, X of them can cleave disulfide bond, and Y of them can react with…
  查看 AI 詳解 →
• 112年 hce_kmu 第69題
  How many of the followings are ketogenic amino acid in human? Asp; Phe; Arg; Val; His; Thr; Lys.
  查看 AI 詳解 →
• 112年 hce_kmu 第73題
  The thickness of endoplasmic reticulum membrane is about 37.5 Å. Which one of the followings is clos…
  查看 AI 詳解 →
• 112年 hce_kmu 第76題
  Which of the followings describes the initial bond formation in the covalent intermediate in the rea…
  查看 AI 詳解 →
• 112年 hce_kmu 第78題
  What is an important component(s) to transport ammonia from skeletal muscles and the other tissues t…
  查看 AI 詳解 →
• 112年 hce_kmu 第80題
  A young boy is unusually tall and presents with joint laxity and retinal detachment. Examination rev…
  查看 AI 詳解 →
• 112年 hce_kmu 第82題
  What is the main pharmacological action of benzoate and phenylbutyrate, which are used to treat urea…
  查看 AI 詳解 →
• 111年 hce_kmu 第19題
  Which amino acid side chain has the highest pKa?
  查看 AI 詳解 →
• 111年 hce_kmu 第29題
  Which of the following pairs about the accumulated molecules and metabolic disorder is NOT correct?
  查看 AI 詳解 →
• 111年 hce_kmu 第72題
  The molecular weight of Protein A (pI = 4.0), B (pI = 6.8), and C (pI = 8.5) is 14 kDa, 24 kDa, and…
  查看 AI 詳解 →
• 111年 hce_kmu 第74題
  (1) Arg; (2) Asp; (3) Gly; (4) Cys; (5) His; (6) Ser; (7) Thr. Which of the followings does NOT appe…
  查看 AI 詳解 →
• 111年 hce_kmu 第87題
  Amino acids can be classified into different groups based on the R-group structure. Which class of a…
  查看 AI 詳解 →
• 110年 hce_kmu 第17題
  Which of the following chemicals is allosteric activator of carbamoyl phosphate synthetase I?
  查看 AI 詳解 →
• 110年 hce_kmu 第20題
  Glutamate is metabolically converted to α-ketoglutarate and $NH_4^+$ in mitochondria matrix of hepat…
  查看 AI 詳解 →
• 110年 hce_kmu 第22題
  Which one of these characteristics is FALSE for the α-helix in protein?
  查看 AI 詳解 →

• 110年 hce_kmu 第61題
  Ribonucleotide reductase catalyzes the reduction of ribonucleotides to deoxyribonucleotides. Which o…
  查看 AI 詳解 →
• 110年 hce_kmu 第75題
  Which of the following statements about amino acids is CORRECT? ① Methionine is sulfur-containing am…
  查看 AI 詳解 →
• 110年 hce_kmu 第76題
  Which of the following enzymes are aspartate protease ? ① Subtilisin; ② Cathepsin D; ③ HIV-protease;…
  查看 AI 詳解 →
• 110年 hce_kmu 第77題
  Which of the following statements for the structure of proteins are CORRECT? ① A bond between amino…
  查看 AI 詳解 →
• 110年 hce_kmu 第88題
  A peptide is digested by chymotrypsin, and the resulting peptides are shown as following: Gly-Asn; A…
  查看 AI 詳解 →
• 109年 hce_kmu 第16題
  Which of the following amino acid side chains has the highest $pK_a$ value?
  查看 AI 詳解 →
• 109年 hce_kmu 第17題
  In the active site of chymotrypsin, which of the following is the amino acid residue arrangement ord…
  查看 AI 詳解 →
• 109年 hce_kmu 第19題
  Poly-lysine exhibits a random coil structure at neutral pH. What kind of interaction can cause its f…
  查看 AI 詳解 →
• 109年 hce_kmu 第27題
  Which of the following is the building block for the biosynthesis of phenylalanine, tyrosine, and tr…
  查看 AI 詳解 →
• 109年 hce_kmu 第83題
  Which of the polypeptide is most likely to form a collagen structure?
  查看 AI 詳解 →
• 109年 hce_kmu 第85題
  Proline residues are infrequently found in ________due to their ________.
  查看 AI 詳解 →
• 109年 hce_kmu 第86題
  When oxygen is bound to myoglobin, the amino acid ________ is complexed to the iron ion of the heme…
  查看 AI 詳解 →
• 109年 hce_kmu 第87題
  Which of the following is associated for determining the dihedral angle (phi) of the peptide bonds?
  查看 AI 詳解 →
• 108年 hce_kmu 第22題
  Which of the metabolites in the urea cycle is linked to the citric acid cycle?
  查看 AI 詳解 →
• 108年 hce_kmu 第29題
  Histones are found in eukaryotic cell nuclei that package and order the DNA into structural units ca…
  查看 AI 詳解 →
• 108年 hce_kmu 第61題
  A mixture of four amino acids is separated by using a cation exchanger with an elution gradient of i…
  查看 AI 詳解 →
• 108年 hce_kmu 第62題
  For an $\alpha$-helix has the sequence : $^+H_3N$-Asp-Trp-Gln-Leu-His-Val-Phe-Ala-Lys-Val-Glu-$COO^-$…
  查看 AI 詳解 →
• 108年 hce_kmu 第63題
  The carbohydrate moiety is always attached to glycoproteins through _______.
  查看 AI 詳解 →
• 108年 hce_kmu 第76題
  Degradation of amino acids can produce the precursors that are used to synthesize glucose or convert…
  查看 AI 詳解 →
• 108年 hce_kmu 第78題
  Defect in metabolism of phenylalanine causes phenylketounia and alkaptonuria. Which of the following…
  查看 AI 詳解 →
• 107年 hce_kmu 第16題
  ________ are commonly referred to, respectively, as the $21^{st}$ and $22^{nd}$ amino acids.
  查看 AI 詳解 →
• 107年 hce_kmu 第24題
  Which of the following peptides has the largest molar extinction coefficient for UV absorption at 28…
  查看 AI 詳解 →
• 107年 hce_kmu 第26題
  What enzyme can generate citrulline?
  查看 AI 詳解 →
• 107年 hce_kmu 第28題
  What amino acid residue is required for the protein region to interact with Src homology 3 (SH3) dom…
  查看 AI 詳解 →
• 107年 hce_kmu 第29題
  Molecular chaperones assist proteins in the formation of ________.
  查看 AI 詳解 →
• 107年 hce_kmu 第73題
  What amino acid residues in some membrane-associated proteins are covalently linked to myristoyl or…
  查看 AI 詳解 →
• 107年 hce_kmu 第79題
  Which of the following amino acids belong to ketogenic and glucogenic? (a) Trp (b) Phe (c) Tyr (d) A…
  查看 AI 詳解 →
• 107年 hce_kmu 第86題
  The peptide QYDG has a N-terminal _______ residue.
  查看 AI 詳解 →
• 107年 hce_kmu 第89題
  Chymotrypsin, a serine protease, preferentially cleaves a peptide bond adjoining a bulky non-polar s…
  查看 AI 詳解 →
• 106年 hce_kmu 第25題
  Which of the following amino acids is a key gluconeogenic amino acid that is synthesized in muscle b…
  查看 AI 詳解 →
• 106年 hce_kmu 第28題
  What following amino acid residues in some proteins can be hydroxylated?
  查看 AI 詳解 →
• 106年 hce_kmu 第30題
  If the isoelectric point (pI) of a protein is 5.8 at buffer pH=7.5, how is the protein electrically…
  查看 AI 詳解 →
• 106年 hce_kmu 第64題
  Which one of the representations describes the oligopeptide shown below?
  查看 AI 詳解 →
• 106年 hce_kmu 第77題
  Which of the following statements about urea cycle are correct? A Urea is the end product of the ure…
  查看 AI 詳解 →
• 106年 hce_kmu 第88題
  Collagen is the most abundant protein with over 28 distinct types in the animal world. What are the…
  查看 AI 詳解 →
• 106年 hce_kmu 第89題
  What two amino acids can be directly converted each other by a single biochemical reaction?
  查看 AI 詳解 →
• 106年 hce_kmu 第90題
  Which of the following statements about proteins is correct?
  查看 AI 詳解 →
• 105年 hce_kmu 第33題
  Which of the following characteristics best describes the urea cycle?
  查看 AI 詳解 →
• 104年 hce_kmu 第47題
  Which of the following proteins have quaternary structure? I. Methionine II. Lysozyme III. Collagen…
  查看 AI 詳解 →
• 104年 hce_kmu 第79題
  Which peptide can form disulfide bond and has high absorbance at 280 nm?
  查看 AI 詳解 →